Tieteelliset tutkimukset

  • Tieteelliset tutkimukset osoittavat Actimelin vaikuttavan suoliston limakalvoon.
  • Lisäksi muita tieteellisiä tutkimuksia Actimelin terveysvaikutuksista.

    • Tieteelliset tutkimukset osoittavat Actimelin vaikuttavan suoliston limakalvoon.

    Kirjoittajat Otsikko Linkki artikkeliin
    Parassol N, Freitas M, Thoreux K, Dalmasso G, Bourdet-Sicard R, Rampal P. Lactobacillus casei DN-114 001 inhibits the increase in paracellular permeability of enteropathogenic Escherichia coli-infected T84 cells. Res Microbiol. 2005 Mar;156(2):256-62.
    Freitas M, Tavan E, Cayuela C, Diop L, Sapin C, Trugnan G. Host-pathogens cross-talk. Indigenous bacteria and probiotics also play the game. Biol Cell. 2003 Nov;95(8):503-6.
    Thoreux K, Balas D, Bouley C, Senegas-Balas F. Diet supplemented with yoghurt or milk fermented by Lactobacillus casei DN-114 001 stimulates growth and brush-border enzyme activities in mouse small intestine. Digestion. 1998 Jul-Aug;59(4):349-59.
    Thoreux K, Senegas-Balas F, Bernard-Perrone F, Giannarelli S, Denariaz G, Bouley C, Balas D. Modulation of proliferation, second messenger levels, and morphotype expression of the rat intestinal epithelial cell line IEC-6 by fermented milk J Dairy Sci. 1996 Jan;79(1):33-43.

    Lisäksi muita tieteellisiä tutkimuksia Actimelin terveysvaikutuksista.

    Kirjoittajat Otsikko Linkki artikkeliin
    de Moreno de LeBlanc A, Dogi CA, Galdeano CM, Carmuega E, Weill R, Perdigón G. Effect of the administration of a fermented milk containing Lactobacillus casei DN-114001 on intestinal microbiota and gut associated immune cells of nursing mice and after weaning until immune maturity BMC Immunol. 2008 Jun 13;9:27
    Llopis M, Antolin M, Carol M, Borruel N, Casellas F, Martinez C, Espín-Basany E, Guarner F, Malagelada JR. Lactobacillus casei downregulates commensals' inflammatory signals in Crohn's disease mucosa. Inflamm Bowel Dis. 2008 Oct 6;15(2):275-283.
    de Moreno de LeBlanc A, Chaves S, Carmuega E, Weill R, Antóine J, Perdigón G. Effect of long-term continuous consumption of fermented milk containing probiotic bacteria on mucosal immunity and the activity of peritoneal macrophages. Immunobiology. 2008;213(2):97-108.
    Baba N, Samson S, Bourdet-Sicard R, Rubio M, Sarfati M. Commensal bacteria trigger a full dendritic cell maturation program that promotes the expansion of non-Tr1 suppressor T cells. J Leukoc Biol. 2008 Aug;84(2):468-76.
    Amital H, Gilburd B, Shoenfeld Y. Probiotic supplementation with Lactobacillus casei (Actimel) induces a Th1 response in an animal model of antiphospholipid syndrome. Ann N Y Acad Sci. 2007 Sep;1110:661-9.
    Kokesová A, Frolová L, Kverka M, Sokol D, Rossmann P, Bártová J, Tlaskalová- Hogenová H. Oral administration of probiotic bacteria (E. coli Nissle , E. coli O83, Lactobacillus casei ) influences the severity of dextran sodium sulfate-induced colitis in BALB/c mice. Folia Microbiol (Praha). 2006;51(5):478-84.
    Angulo S, Llopis M, Antolín M, Gironella M, Sans M, Malagelada JR, Piqué JM, Guarner F, Panés J. Lactobacillus casei prevents the upregulation of ICAM-1 expression and leukocyte recruitment in experimental colitis. Am J Physiol Gastrointest Liver Physiol. 2006 Dec;291(6):G1155-62.
    Carol M, Borruel N, Antolin M, Llopis M, Casellas F, Guarner F, Malagelada JR. Modulation of apoptosis in intestinal lymphocytes by a probiotic bacteria in Crohn's disease. J Leukoc Biol. 2006 May;79(5):917-22.
    Tien MT, Girardin SE, Regnault B, Le Bourhis L, Dillies MA, Coppée JY, Bourdet-Sicard R, Sansonetti PJ, Pédron T. Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells. J Immunol. 2006 Jan 15;176(2):1228-37.
    Fayol-Messaoudi D, Berger CN, Coconnier-Polter MH, Liévin-Le Moal V, Servin AL. pH-, Lactic acid-, and non-lactic acid-dependent activities of probiotic Lactobacilli against Salmonella enterica Serovar Typhimurium. Appl Environ Microbiol. 2005 Oct;71(10):6008-13.
    Llopis M, Antolín M, Guarner F, Salas A, Malagelada JR. Mucosal colonisation with Lactobacillus casei mitigates barrier injury induced by exposure to trinitronbenzene sulphonic acid. Gut. 2005 Jul;54(7):955-9.
    Ingrassia I, Leplingard A, Darfeuille-Michaud A. Lactobacillus casei DN-114 001 inhibits the ability of adherent-invasive Escherichia coli isolated from Crohn's disease patients to adhere to and to invade intestinal epithelial cells. Appl Environ Microbiol. 2005 Jun;71(6):2880-7.
    Medici M, Vinderola CG, Weill R, Perdigón G. Effect of fermented milk containing probiotic bacteria in the prevention of an enteroinvasive Escherichia coli infection in mice. J Dairy Res. 2005 May;72(2):243-9.
    Oozeer R, Furet JP, Goupil-Feuillerat N, Anba J, Mengaud J, Corthier G. Differential activities of four Lactobacillus casei promoters during bacterial transit through the gastrointestinal tracts of human- microbiota-associated mice. Appl Environ Microbiol. 2005 Mar;71(3):1356-63.
    Oozeer R, Mater DD, Goupil-Feuillerat N, Corthier G. Initiation of protein synthesis by a labeled derivative of the Lactobacillus casei DN-114 001 strain during transit from the stomach to the cecum in mice harboring human microbiota. Appl Environ Microbiol. 2004 Dec;70(12):6992-7.
    Chapat L, Chemin K, Dubois B, Bourdet-Sicard R, Kaiserlian D. Lactobacillus casei reduces CD8+ T cell-mediated skin inflammation. Eur J Immunol. 2004 Sep;34(9):2520-8.
    Borruel N, Casellas F, Antolín M, Llopis M, Carol M, Espíin E, Naval J, Guarner F, Malagelada JR. Effects of nonpathogenic bacteria on cytokine secretion by human intestinal mucosa. Am J Gastroenterol. 2003 Apr;98(4):865-70.
    Borruel N, Carol M, Casellas F, Antolín M, de Lara F, Espín E, Naval J, Guarner F, Malagelada JR. Increased mucosal tumour necrosis factor alpha production in Crohn's disease can be downregulated ex vivo by probiotic bacteria. Gut. 2002 Nov;51(5):659-64.
    Oozeer R, Goupil-Feuillerat N, Alpert CA, van de Guchte M, Anba J, Mengaud J, Corthier G. Lactobacillus casei is able to survive and initiate protein synthesis during its transit in the digestive tract of human flora-associated mice. Appl Environ Microbiol. 2002 Jul;68(7):3570-4.
    Guérin-Danan C, Meslin JC, Chambard A, Charpilienne A, Relano P, Bouley C, Cohen J, Andrieux C. Food supplementation with milk fermented by Lactobacillus casei DN-114 001 protects suckling rats from rotavirus-associated diarrhea. J Nutr. 2001 Jan;131(1):111-7.
    Djouzi Z, Andrieux C, Degivry MC, Bouley C, Szylit O. The association of yogurt starters with Lactobacillus casei DN 114.001 in fermented milk alters the composition and metabolism of intestinal microflora in germ-free rats and in human flora-associated rats. J Nutr. 1997 Nov;127(11):2260-6.